Deatailed information for cohesin site CDBP00416185

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  • Basic information
  • CohesinDB ID: CDBP00416185
  • Locus: chr21-29305747-29309169
  • Data sourse: ENCSR000DZP, ENCSR230ZWH, GSE98367, GSE138405, ENCSR879KXD, ShirahigeLab, ShirahigeLab-NatGen2015, GSE62063, GSE120943, ENCSR153HNT, GSE103477, GSE126755, GSE165895
  • Cell type: MDM, RPE, Hela-Kyoto, Fibroblast, Monocytes, GM12878, Ramos, K-562, Liver, Neutrophil, Macrophage, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.867
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 68% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 46%, "7_Enh": 34%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, HMG20A, ZNF660, ZSCAN5C, SOX2, MEIS2, NME2, FOXA1, PBX2, HDGF, ATF3, NFIC, RUNX3, PRDM1, ZBTB44, CBFB, ZNF189, SMARCE1, ZSCAN4, MZF1, ZNF467, JMJD1C, ELF1, TRIM28, TEAD1, BCLAF1, ESR1, HDAC8, ZFP91, CTCF, MNT, ZNF260, PYGO2, DPF2, TRIM24, SOX6, E2F1, TEAD4, FOXA3, ZNF175, GATAD2A, EHMT2, RBPJ, EED, GLIS1, POU2F2, CHD8, POU5F1, TOP2A, ID3, CTBP1, MTA2, ZSCAN21, ZBTB17, STAT1, SRF, SAP130, NBN, ARID3A, ERG2, HIC1, ERG, MIER1, ZNF341, ONECUT1, MYC, SMARCA4, ARID1B, RAD21, DNMT1, GRHL3, NKX2-1, FOXK2, GABPA, ZNF614, IKZF1, MIER3, RCOR1, ZNF639, NFRKB, ARNTL, NR2F6, ESRRA, CEBPB, KMT2A, EZH2, FEZF1, ZHX2, SPI1, MIXL1, IRF1, HDAC2, GATA2, FLI1, NR2C2, RELB, NFIL3, CC2D1A, RUNX1, BCL6, HDAC1, CEBPA, NKX2-2, SOX13, ERG3, TRIM22, ZNF18, MEF2A, RARA, ZNF384, ZBTB2, CREBBP, BRD9, RUNX2, CDK6, GATA4, OSR2, ZNF184, BACH1, ATF2, PRDM9, ZEB2, HMBOX1, FOXM1, CBFA2T3, NR2C1, SMARCB1, SUPT5H, CDK8, ZNF10, MED1, TEAD3, TERF1, ZNF558, PML, SCRT2, PIAS1, SUPT16H, NCOA1, STAT5A, RBM22, NUP98-HOXA9, BCL11A, HNF4A, ZBTB7A, RBM25, ATF7, HOXA9, PHIP, BCOR, FOXP1, PRDM6, NCOR2, MLLT1, PTTG1, NFATC3, MEF2B, FOXA2, MTA3, EBF1, CREM, NFATC1, ZNF600, ZBTB33, MEF2C, HOXB13, ZNF318, KDM1A, YY1, RELA, TARDBP, JUNB, ZFP36, HIF1A, OTX2, GATA3, BATF, MAX, GATA1, ZNF143, TLE3, ZFP69B, CEBPG, ZNF592, NCOA3, NR2F2, SP7, NR2F1, PKNOX1, ELF3, ARID4B, AR, BHLHE40, TAF1, ZBTB40, ZNF324, ZNF366, EGR1, NCOR1, IKZF2, JUND, BRD4, SCRT1, ZNF24
  • Target gene symbol (double-evidenced CRMs): CCT8,USP16,MAP3K7CL,BACH1
  • Function elements
  • Human SNPs: Creatine_kinase_levels
  • Number of somatic mutations (coding): 46
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000156256, ENSG00000156261, ENSG00000156265, ENSG00000156273,
  • Related loop: chr21:29050000-29075000~~chr21:29300000-29325000, chr21:29089325-29091118~~chr21:29297646-29300784, chr21:29162305-29165453~~chr21:29297767-29300990, chr21:29162310-29165464~~chr21:29297711-29300996, chr21:29162377-29165492~~chr21:29297770-29301094, chr21:29163333-29165304~~chr21:29297741-29300792, chr21:29163629-29165264~~chr21:29297785-29301017, chr21:29175000-29200000~~chr21:29300000-29325000, chr21:29181177-29183351~~chr21:29297767-29300990, chr21:29195502-29197292~~chr21:29297767-29300990, chr21:29232806-29234518~~chr21:29297832-29300927, chr21:29300000-29325000~~chr21:33200000-33225000,
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