Deatailed information for cohesin site CDBP00416189


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00416189
  • Locus: chr21-29318199-29318712
  • Data sourse: GSE116344, ENCSR153HNT
  • Cell type: K-562, RH4
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 68% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 56%, "7_Enh": 26%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: CHD8, ZNF263, NFATC1, ZFX, ZNF692, ZBTB48, FOXA1, LEO1, RELA, ASCL1, NEUROD1, RUNX2, NFIC, MYC, PRDM1, TCF4, HIF1A, GRHL3, OTX2, BHLHE22, MAX, CBFA2T3, ZNF143, GATA1, SUPT5H, ZFP69B, CEBPB, NCOA3, TRIM28, NEUROG2, SUPT16H, EZH2, LMO2, OCA2, GRHL2, MYOD1, CTCF, RBM22, AR, GATA6, FLI1, BRD4, CLOCK, PDX1, AHR
  • Target gene symbol (double-evidenced CRMs): CCT8,BACH1,MAP3K7CL,USP16
  • Function elements
  • Human SNPs: Body_mass_index
  • Number of somatic mutations (coding): 8
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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