- Basic information
- CohesinDB ID: CDBP00416196
- Locus: chr21-29323911-29324647
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE120943, GSE98367
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Cell type: RPE, Fibroblast, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 70%,
"4_Tx": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, MAFG, ZFX, DUX4, MAFF, FOXA1, DDX5, CDK9, KDM1A, RELA, RAD21, OTX2, ZSCAN4, VDR, JMJD1C, C11orf30, CTCF, RBM22, SPI1, HNF4A, ZNF644, ZNF146, BRD4, NCOR2, MLLT1, ZNF316
- Target gene symbol (double-evidenced CRMs): USP16,MAP3K7CL,CCT8,BACH1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000156256,
ENSG00000156261,
ENSG00000156265,
ENSG00000156273,
- Related loop:
chr21:29050000-29075000~~chr21:29300000-29325000,
chr21:29075000-29100000~~chr21:29325000-29350000,
chr21:29150000-29175000~~chr21:29325000-29350000,
chr21:29175000-29200000~~chr21:29300000-29325000,
chr21:29225000-29250000~~chr21:29325000-29350000,
chr21:29300000-29325000~~chr21:33200000-33225000,