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Basic information

CohesinDB ID: CDBP00415540

Locus: chr21-26709227-26709736

Data sourse: GSE116344, ShirahigeLab-NatGen2015

Cell type: Fibroblast, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 83%, "14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, NFKB2, JUNB, RUNX2, ZFX, PBX4, BRD4, SMAD3, BATF3, NFKB1, RELB, DDX5, JUN, FOS, HOXC5, FOSL2

Target gene symbol (double-evidenced CRMs): MRPL39,GABPA,CYYR1,ADAMTS1,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154727, ENSG00000142192, ENSG00000166265, ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415540