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Basic information

CohesinDB ID: CDBP00415267

Locus: chr21-25600851-25601124

Data sourse: GSE206145, GSE206145-NatGen2015

Cell type: RPE, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 61% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 49%, "4_Tx": 48%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU5F1, TOP2A, PAF1, SOX2, XBP1, ZBTB48, FOXA1, RBFOX2, ZNF300, ATF3, MYC, ISL1, PRDM1, GRHL3, SOX11, GABPA, TP63, NKX3-1, SUPT5H, GATA1, HAND2, ESR1, HNF1B, TP53, PHOX2B, ELF3, SPI1, BCL11A, ZNF664, AR, RBM25, BRD4, FOXP1, AHR

Target gene symbol (double-evidenced CRMs): CYYR1,ADAMTS1,ATP5PF,APP,MRPL39,GABPA,JAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154723, ENSG00000154727, ENSG00000142192, ENSG00000166265, ENSG00000154734,

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Deatailed information for cohesin site CDBP00415267