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Basic information

CohesinDB ID: CDBP00415426

Locus: chr21-26154777-26155253

Data sourse: GSE206145, GSE116344

Cell type: RPE, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 62%, "15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ASCL1, PAF1, HNF1A, HNF1B, PHIP, NKX2-1, MYOD1, TWIST1

Target gene symbol (double-evidenced CRMs): GABPA,APP,JAM2,ADAMTS1,CYYR1,MRPL39

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154727, ENSG00000142192, ENSG00000166265, ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415426