Deatailed information for gene ENSG00000185272
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00015928
- Gene Symbol: RBM11
- Ensembl ID: ENSG00000185272
-
Gene locus: chr21:14216129-14228372
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-13806228-13807204,
chr21-13809209-13809482,
chr21-13810125-13810345,
chr21-13816164-13816623,
chr21-14026851-14028433,
chr21-14030739-14031244,
chr21-14031633-14031954,
chr21-14047133-14047213,
chr21-14130738-14131176,
chr21-14215832-14216924,
chr21-14362036-14362277,
chr21-14362949-14363444,
chr21-14366465-14366972,
chr21-14376765-14377390,
chr21-14378678-14379134,
chr21-14382340-14384384,
chr21-14389947-14390070,
chr21-14524873-14526196,
chr21-14526494-14529969,
chr21-14530357-14536642,
chr21-14537276-14539605,
chr21-14541246-14550672,
chr21-14731536-14731839,
chr21-14733310-14733532,
chr21-14733859-14734983,
chr21-14735214-14740505,
chr21-14741240-14741827,
chr21-14742627-14743253,
chr21-14743590-14745739,
chr21-14751049-14751687,
chr21-14752293-14755665,
chr21-14757628-14757997,
chr21-14762012-14763864,
chr21-14764487-14764787,
chr21-14765555-14765610,
chr21-14766150-14766779,
chr21-14768089-14768942,
chr21-14771132-14775232,
chr21-14776599-14776961,
chr21-14777435-14777640,
chr21-14779142-14779611,
chr21-14789081-14789506,
chr21-14949802-14950014,
chr21-14952341-14953601,
chr21-14953826-14954137,
chr21-14955906-14957615,
chr21-14957952-14958563,
chr21-14959237-14960295,
chr21-14968863-14969588,
chr21-15149683-15150166,
chr21-15151490-15152324,
chr21-15155413-15155883,
chr21-15159358-15159865,
chr21-15163125-15163429,
chr21-15164026-15164374,
chr21-15164670-15165346,
chr21-15171644-15171827,
chr21-15172374-15174253,
chr21-15455633-15456680,
chr21-15468364-15468759,
chr21-15470766-15470841,
chr21-15471943-15472539,
chr21-15480544-15485701,
chr21-15486435-15487318,
chr21-15495910-15496512,
-
Co-expression with cohesin genes Rho = 0.3243
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.527
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.888
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: HEK293T,Liver,RT-112,K-562,H1-hESC,HFF-hTERT,HeLa-S3,H9-hESC,H1-Mesenchymal,H1-Mesendoderm
- Related loop:
chr21:13800000-13825000~~chr21:14225000-14250000,
chr21:14025000-14050000~~chr21:14225000-14250000,
chr21:14125000-14150000~~chr21:14225000-14250000,
chr21:14225000-14250000~~chr21:14350000-14375000,
chr21:14225000-14250000~~chr21:14375000-14400000,
chr21:14225000-14250000~~chr21:14525000-14550000,
chr21:14225000-14250000~~chr21:14725000-14750000,
chr21:14225000-14250000~~chr21:14750000-14775000,
chr21:14225000-14250000~~chr21:14775000-14800000,
chr21:14225000-14250000~~chr21:14950000-14975000,
chr21:14225000-14250000~~chr21:15150000-15175000,
chr21:14225000-14250000~~chr21:15450000-15475000,
chr21:14225000-14250000~~chr21:15475000-15500000,
- Cohesin-loop type: HiC,Direct
- Cohesin-loop study:
GSE44267, 4DNFI8649RQJ, GSE52457, 4DNFIPAF4PYT, Direct, 4DNFIFI6NIKJ, 4DNFIE8E4ANZ, GSE105028, 4DNFIB7QTIMH, 4DNFIBN9K4V9, 4DNFIDBIEXI7, ENCSR545YBD, GSE155380, GSE58752
- Cohesin-loop subunit: Other
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: CMK,SLK
- Cohesin-DEGs, number of studies: 3
- Cohesin-DEGs, study: GSE154086,GSE138937
- Cohesin-DEGs, subunit: CTCF,Rad21,SA2