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Basic information

CohesinDB ID: CDBG00017894

Gene Symbol: LTN1

Ensembl ID: ENSG00000198862

Gene locus: chr21:28928143-28992956 Strand: -

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-27330294-27330541, chr21-27332919-27333530, chr21-27338733-27339220, chr21-27339748-27340390, chr21-27342759-27343046, chr21-27344243-27344606, chr21-27345866-27347069, chr21-27555979-27556487, chr21-27557265-27557849, chr21-27561020-27561913, chr21-27563002-27566992, chr21-27567650-27574605, chr21-27697831-27705094, chr21-27719405-27719658, chr21-27722043-27722380, chr21-27758206-27760949, chr21-27763406-27763661, chr21-27767939-27768663, chr21-27771982-27772448, chr21-27772650-27773277, chr21-28050232-28054706, chr21-28055025-28055673, chr21-28057219-28057369, chr21-28058256-28059473, chr21-28060090-28060269, chr21-28062272-28062979, chr21-28064474-28066923, chr21-28067534-28068121, chr21-28068492-28070097, chr21-28075497-28075714, chr21-28077708-28078583, chr21-28078861-28079357, chr21-28083442-28083953, chr21-28086967-28087606, chr21-28089554-28090626, chr21-28091804-28092882, chr21-28093892-28094245, chr21-28094978-28096008, chr21-28096286-28096525, chr21-28097109-28097588, chr21-28097845-28098106, chr21-28098567-28098840, chr21-28099075-28100393, chr21-28177209-28177514, chr21-28184738-28184897, chr21-28191829-28192284, chr21-28192770-28193616, chr21-28196422-28197023, chr21-28325514-28326311, chr21-28332778-28340251, chr21-28341277-28341586, chr21-28342232-28342714, chr21-28343843-28344097, chr21-28501658-28501980, chr21-28509074-28509343, chr21-28515785-28518121, chr21-28518339-28518971, chr21-28519958-28520245, chr21-28520608-28523119, chr21-28523395-28523853, chr21-28536526-28542170, chr21-28543998-28544380, chr21-28547810-28548217, chr21-28549840-28550779, chr21-28581117-28581680, chr21-28587521-28588238, chr21-28589885-28590379, chr21-28590711-28591217, chr21-28595856-28596319, chr21-28726042-28726237, chr21-28728325-28728960, chr21-28730369-28730658, chr21-28734874-28735184, chr21-28737724-28738809, chr21-28739033-28739334, chr21-28740627-28747447, chr21-28749634-28749909, chr21-28750506-28751239, chr21-28754026-28755278, chr21-28761675-28762116, chr21-28763422-28763635, chr21-28770813-28772668, chr21-28773018-28773359, chr21-28776171-28776936, chr21-28780249-28780552, chr21-28781296-28782228, chr21-28783216-28784241, chr21-28788029-28788392, chr21-28789591-28789962, chr21-28791522-28791992, chr21-28792476-28795005, chr21-28797075-28797529, chr21-28798715-28799054, chr21-28801989-28802317, chr21-28805505-28806589, chr21-28818509-28819160, chr21-28819578-28819844, chr21-28821326-28823536, chr21-28871320-28872051, chr21-28923471-28923837, chr21-28931049-28931107, chr21-28938796-28941472, chr21-28944300-28944655, chr21-28951723-28951953, chr21-28959314-28959751, chr21-28961868-28962960, chr21-28968738-28969112, chr21-28975272-28975803, chr21-28977017-28977868, chr21-28987587-28988460, chr21-28991009-28991435, chr21-28991642-28993980, chr21-29018321-29020227, chr21-29023611-29026769, chr21-29051564-29051818, chr21-29053116-29053515, chr21-29054263-29054943, chr21-29057293-29057849, chr21-29058619-29059007, chr21-29063826-29064273, chr21-29064621-29065502, chr21-29066238-29066599, chr21-29071350-29071693, chr21-29072018-29074622, chr21-29074884-29075433,

Co-expression with cohesin genes Rho = 0.7256 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.269
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.891
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: IMR-90,MB157,GM12892,K1,H1-Mesendoderm,Olfactory,Hepatocyte-H9,HEK293T,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,H1-Trophectoderm,SU-DHL-2,H9-hESC,ARPE-19,Hep-G2,H1-hESC,HT-1376,MSLCL,BMEC,SU-DHL-4,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Jurkat,CC-2551,CyT49-Gut,HAP1,HFF-hTERT

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: 4DNFIQWD8ZYD, 4DNFI8649RQJ, 4DNFI3CFMRID, ENCSR194SRI, GSE43070, 4DNFIMROE6N4, 4DNFITUOMFUQ, 4DNFIE8E4ANZ, GSE116869, 4DNFI5SUHCGZ, ENCSR545YBD, ENCSR852KQC, GSE120294, ENCSR361AYD, ENCSR146FPM, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFI6EIFUZI, 4DNFIA6NSSBJ, 4DNFIREVU1Z5, 4DNFII6AN691, 4DNFIRKGMZRQ, ENCSR668RDP, ENCSR381DCY, 4DNFIHN2QSMX, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR981FNA, ENCSR587DSF, ENCSR452NHL, 4DNFICEGAHRC, 4DNFI1E6NJQJ, ENCSR128RPG, GSE52457, ENCSR507AHE, 4DNFI3A3VYWU, ENCSR658RQQ, Direct, ENCSR314HAC, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFIX7H3CE2, 4DNFIYDBBSE3, 4DNFI1UEG1HD, 4DNFII84FBKM, 4DNFIYIAUEPW, 4DNFIEJEFCAM, ENCSR244BBG, GSE44267, 4DNFI9815EEJ, 4DNFIC3HAU11, ENCSR247RGI, ENCSR110JOO, 4DNFIVJ3IIQL, 4DNFIQ2687RT, ENCSR933UZH, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, GSE105028, 4DNFIBKZK63V, 4DNFIH7TH4MF, ENCSR033GUP

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: SLK,P3HR-1,K-562,Kelly,HeLa-S3

Cohesin-DEGs, number of studies: 8

Cohesin-DEGs, study: GSE115253,GSE140651,GSE138937,GSE131448,GSE108869,GSE130558

Cohesin-DEGs, subunit: SA2,WAPL,CTCF,SMC1,Rad21,BORIS

eachgene

Deatailed information for gene ENSG00000198862