Deatailed information for gene ENSG00000155313
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009855
- Gene Symbol: USP25
- Ensembl ID: ENSG00000155313
-
Gene locus: chr21:15730024-15880069
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-14074982-14076805,
chr21-14078786-14079337,
chr21-14081972-14082588,
chr21-14083193-14085404,
chr21-14086133-14086946,
chr21-14087731-14088065,
chr21-14088528-14088691,
chr21-14092884-14093529,
chr21-14095068-14096724,
chr21-14097913-14098387,
chr21-14250162-14250413,
chr21-14253316-14254447,
chr21-14256459-14256802,
chr21-14257889-14261023,
chr21-14270403-14271030,
chr21-14273688-14274371,
chr21-14376765-14377390,
chr21-14378678-14379134,
chr21-14382340-14384384,
chr21-14389947-14390070,
chr21-14875513-14876818,
chr21-14877231-14881713,
chr21-14884719-14885074,
chr21-14886972-14889717,
chr21-14891154-14892018,
chr21-14892252-14892703,
chr21-14897736-14898129,
chr21-14977644-14978098,
chr21-14979219-14979633,
chr21-14981349-14981523,
chr21-14984759-14985835,
chr21-14989089-14989683,
chr21-14991983-14992261,
chr21-14994087-14994394,
chr21-14995418-14997309,
chr21-14999736-15000684,
chr21-15050583-15051369,
chr21-15051819-15053037,
chr21-15054708-15055248,
chr21-15057205-15057843,
chr21-15058151-15060232,
chr21-15060514-15067444,
chr21-15069437-15070135,
chr21-15071057-15071570,
chr21-15073893-15074094,
chr21-15513318-15515205,
chr21-15515799-15516316,
chr21-15519391-15519539,
chr21-15520334-15522556,
chr21-15585495-15588247,
chr21-15590091-15590381,
chr21-15590652-15594426,
chr21-15596889-15597197,
chr21-15601722-15602750,
chr21-15603827-15604974,
chr21-15605222-15605521,
chr21-15606019-15606774,
chr21-15610467-15610826,
chr21-15614967-15615288,
chr21-15616932-15619309,
chr21-15620069-15620305,
chr21-15620844-15621426,
chr21-15625483-15625696,
chr21-15628195-15629865,
chr21-15631324-15631811,
chr21-15632482-15633404,
chr21-15639024-15639642,
chr21-15640705-15640865,
chr21-15679498-15680381,
chr21-15682026-15683675,
chr21-15726005-15726347,
chr21-15726744-15727018,
chr21-15728664-15733925,
chr21-15734927-15736334,
chr21-15737261-15737766,
chr21-15741172-15745156,
chr21-15748731-15750124,
chr21-15751171-15751521,
chr21-15752991-15753477,
chr21-15754315-15755248,
chr21-15761470-15761961,
chr21-15765980-15766151,
chr21-15767110-15767258,
chr21-15768157-15768884,
chr21-15774442-15775435,
chr21-15775679-15776594,
chr21-15779389-15779797,
chr21-15781953-15782661,
chr21-15783756-15783972,
chr21-15788870-15789636,
chr21-15797689-15798352,
chr21-15799256-15799786,
chr21-15801204-15801900,
chr21-15804362-15804554,
chr21-15807461-15807690,
chr21-15809823-15810205,
chr21-15812438-15812641,
chr21-15814958-15815592,
chr21-15820922-15821240,
chr21-15824259-15827480,
chr21-15827702-15827852,
chr21-15828618-15828901,
chr21-15834852-15835348,
chr21-15837530-15838161,
chr21-15841385-15842641,
chr21-15845569-15846660,
chr21-15848382-15849717,
chr21-15850634-15851036,
chr21-15854171-15854394,
chr21-15856475-15856816,
chr21-15869749-15869932,
chr21-15872610-15873025,
chr21-15873591-15873807,
chr21-15876479-15876649,
chr21-16001861-16004507,
chr21-16004906-16005266,
chr21-16005991-16006690,
chr21-16020923-16021229,
chr21-16079014-16079363,
chr21-16079564-16080614,
chr21-16080918-16087159,
chr21-16087918-16088278,
chr21-16091569-16091892,
chr21-16094228-16094605,
chr21-16095161-16095345,
chr21-16179066-16180618,
chr21-16181053-16181397,
chr21-16182009-16182569,
chr21-16184082-16184512,
chr21-16185564-16186135,
chr21-16186787-16187211,
chr21-16187950-16188513,
chr21-16189420-16189727,
chr21-16192814-16197732,
chr21-16198035-16199514,
chr21-16199967-16200171,
chr21-16275469-16276010,
chr21-16278935-16281446,
chr21-16281661-16282184,
chr21-16282871-16283166,
chr21-16284608-16285086,
chr21-16290319-16290597,
chr21-16291430-16291616,
chr21-16295739-16296369,
chr21-16299142-16299640,
chr21-16325876-16326019,
chr21-16328312-16332052,
chr21-16332356-16332972,
chr21-16334182-16334499,
chr21-16342035-16342755,
chr21-16343059-16343480,
chr21-16344700-16345428,
chr21-16347111-16347650,
chr21-16402696-16403231,
chr21-16407671-16408939,
chr21-16409240-16410106,
chr21-16417317-16417443,
chr21-16418688-16425215,
chr21-16604508-16606674,
chr21-16607375-16609815,
chr21-16613408-16613741,
chr21-16619888-16620218,
chr21-16621018-16621349,
chr21-16624524-16624939,
chr21-17051166-17051326,
chr21-17250615-17251384,
chr21-17256094-17256331,
chr21-17263719-17264642,
chr21-17266505-17266907,
chr21-17268861-17271187,
chr21-17271395-17272139,
chr21-17574945-17575093,
chr21-17575466-17576102,
chr21-17579296-17579640,
chr21-17581951-17582360,
chr21-17584154-17587049,
chr21-17592922-17593114,
chr21-17599493-17599842,
chr21-17600958-17601160,
chr21-17602938-17603192,
chr21-17610934-17613664,
chr21-17615995-17616481,
chr21-17774973-17776242,
chr21-17779465-17779881,
chr21-17780265-17781745,
chr21-17781990-17782819,
chr21-17783465-17785440,
chr21-17786174-17786402,
chr21-17786924-17787077,
chr21-17788283-17788550,
chr21-17788766-17789298,
chr21-17789693-17790527,
chr21-17793333-17794084,
chr21-17795350-17796957,
chr21-17797580-17797996,
-
Co-expression with cohesin genes Rho = 0.6410
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.307
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.905
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MB157,DU145,H1-Mesendoderm,Olfactory,HEK293T,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,H9-hESC,Liver,Hep-G2,H1-hESC,HCC1599,MSLCL,SU-DHL-4,NPC-H9,RT-112,HAP1
- Related loop:
chr21:14075000-14100000~~chr21:15725000-15750000,
chr21:14250000-14275000~~chr21:15825000-15850000,
chr21:14375000-14400000~~chr21:15725000-15750000,
chr21:14375000-14400000~~chr21:15800000-15825000,
chr21:14375000-14400000~~chr21:15825000-15850000,
chr21:14375000-14400000~~chr21:15875000-15900000,
chr21:14875000-14900000~~chr21:15725000-15750000,
chr21:14975000-15000000~~chr21:15725000-15750000,
chr21:15050000-15075000~~chr21:15825000-15850000,
chr21:15500000-15525000~~chr21:15825000-15850000,
chr21:15520229-15521680~~chr21:15825383-15827192,
chr21:15520337-15521600~~chr21:15825285-15827222,
chr21:15520438-15521729~~chr21:15825379-15827213,
chr21:15575000-15600000~~chr21:15800000-15825000,
chr21:15591163-15593391~~chr21:15825411-15827711,
chr21:15591857-15593440~~chr21:15825433-15827080,
chr21:15600000-15625000~~chr21:15800000-15825000,
chr21:15600000-15625000~~chr21:15825000-15850000,
chr21:15625000-15650000~~chr21:15725000-15750000,
chr21:15625000-15650000~~chr21:15825000-15850000,
chr21:15678908-15680651~~chr21:15825379-15827213,
chr21:15678925-15680577~~chr21:15825423-15827778,
chr21:15679142-15680653~~chr21:15824955-15827171,
chr21:15681831-15683975~~chr21:15825446-15827214,
chr21:15725000-15750000~~chr21:15825000-15850000,
chr21:15725000-15750000~~chr21:16400000-16425000,
chr21:15725000-15750000~~chr21:17600000-17625000,
chr21:15725000-15750000~~chr21:17775000-17800000,
chr21:15728981-15731357~~chr21:15825379-15827213,
chr21:15729091-15731386~~chr21:15825686-15827611,
chr21:15729281-15731390~~chr21:15825659-15827066,
chr21:15729455-15730632~~chr21:15825625-15827005,
chr21:15729526-15731390~~chr21:15825285-15827222,
chr21:15750000-15775000~~chr21:15850000-15875000,
chr21:15750000-15775000~~chr21:16175000-16200000,
chr21:15750000-15775000~~chr21:17050000-17075000,
chr21:15875000-15900000~~chr21:16000000-16025000,
chr21:15875000-15900000~~chr21:16075000-16100000,
chr21:15875000-15900000~~chr21:16275000-16300000,
chr21:15875000-15900000~~chr21:16325000-16350000,
chr21:15875000-15900000~~chr21:16600000-16625000,
chr21:15875000-15900000~~chr21:17250000-17275000,
chr21:15875000-15900000~~chr21:17575000-17600000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
ENCSR662QKG, GSE95015, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIMROE6N4, 4DNFIE8E4ANZ, ENCSR499RVD, 4DNFIB7QTIMH, GSE116869, 4DNFI5SUHCGZ, ENCSR852KQC, GSE120294, ENCSR672RHL, 4DNFI7H4II2V, ENCSR410MDC, 4DNFIEYQ5ZIR, 4DNFIF2D3TL9, ENCSR113OIR, ENCSR668RDP, 4DNFIBXWIH8J, GSE155380, 4DNFICSTCJQZ, 4DNFICEGAHRC, ENCSR752QCX, ENCSR587DSF, ENCSR452NHL, GSE52457, 4DNFI3A3VYWU, ENCSR658RQQ, Direct, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFI1UEG1HD, GSE116872, ENCSR244BBG, 4DNFIZF1KI43, ENCSR393LOP, GSE44267, 4DNFI9815EEJ, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR338WUS, 4DNFIVJ3IIQL, 4DNFIDKJFK2S, 4DNFIFLJLIS5, GSE105028, 4DNFIDZT7PR8, 4DNFIS5F6EBL, GSE58752, 4DNFIH7TH4MF, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: MCF-7,SLK,OCI-AML-3,K-562,CMK,U2OS,Keratinocytes,CordBlood
- Cohesin-DEGs, number of studies: 9
- Cohesin-DEGs, study: GSE83870,GSE73224,GSE111537,GSE177045,GSE154086,GSE131448,GSE138937,GSE89799
- Cohesin-DEGs, subunit: SMC3,SA2,CTCF,SMC1,Rad21