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Basic information

CohesinDB ID: CDBG00009783

Gene Symbol: C21orf91

Ensembl ID: ENSG00000154642

Gene locus: chr21:17788973-17819356 Strand: -

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-16575404-16575871, chr21-16579540-16580303, chr21-16583550-16584570, chr21-16584776-16585081, chr21-16586117-16589435, chr21-16592201-16592905, chr21-16595785-16596040, chr21-16597851-16598314, chr21-17352342-17352564, chr21-17352941-17353720, chr21-17360708-17361293, chr21-17364021-17364262, chr21-17368762-17369199, chr21-17370093-17370608, chr21-17371078-17371857, chr21-17376067-17376842, chr21-17377529-17377890, chr21-17383874-17384847, chr21-17385065-17389738, chr21-17390128-17390618, chr21-17391038-17391864, chr21-17392847-17393210, chr21-17393972-17394584, chr21-17427928-17429100, chr21-17429707-17430271, chr21-17433211-17433485, chr21-17434658-17435287, chr21-17436920-17439074, chr21-17440398-17441901, chr21-17442241-17442520, chr21-17443841-17444029, chr21-17444297-17444731, chr21-17447844-17448535, chr21-17574945-17575093, chr21-17575466-17576102, chr21-17579296-17579640, chr21-17581951-17582360, chr21-17584154-17587049, chr21-17592922-17593114, chr21-17599493-17599842, chr21-17600958-17601160, chr21-17602938-17603192, chr21-17610934-17613664, chr21-17615995-17616481, chr21-17650364-17650607, chr21-17660473-17661158, chr21-17661485-17661799, chr21-17662469-17662816, chr21-17668672-17669176, chr21-17673220-17674924, chr21-17676688-17681173, chr21-17683768-17683914, chr21-17685520-17685630, chr21-17688607-17690344, chr21-17691367-17691688, chr21-17693819-17694295, chr21-17694563-17695104, chr21-17783465-17785440, chr21-17786174-17786402, chr21-17786924-17787077, chr21-17788283-17788550, chr21-17788766-17789298, chr21-17789693-17790527, chr21-17793333-17794084, chr21-17795350-17796957, chr21-17797580-17797996, chr21-17801315-17801609, chr21-17802147-17803028, chr21-17804509-17804871, chr21-17808054-17808570, chr21-17817153-17820909, chr21-17900339-17904921, chr21-17905247-17905528, chr21-17907747-17907969, chr21-17911083-17912506, chr21-17921425-17922537, chr21-17923497-17927046, chr21-18109406-18109638, chr21-18116584-18116748, chr21-18875172-18876057, chr21-18877363-18878254, chr21-18885261-18885334,

Co-expression with cohesin genes Rho = 0.5938 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.352
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.891
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: TAMR-MCF7,MB157,hTERT-HME1,H1-Mesenchymal,Olfactory,MCF-7,HEK293T,GM12878,K-562,A-549,HFFc6,HeLa-S3,H9-hESC,HCT-116,H1-hESC,HT-1376,Motor-Neuron,NaiveB,HUES64,SU-DHL-4,RT-112,Skin-Fibroblast,CC-2551,HFF-hTERT,HAP1

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: 4DNFI8649RQJ, ENCSR662QKG, GSE95015, 4DNFIWZEN3FF, GSE118716, GSE108787, 4DNFI5SUHCGZ, GSE84022, GSE120294, 4DNFIZ4F74QR, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR866FWQ, ENCSR732QOH, 4DNFIYD8LO9Z, GSE155380, GSE97394, GSE80820, 4DNFI9YAVTI1, GSE52457, ENCSR658RQQ, Direct, 4DNFIXWCLD4M, 4DNFIX7H3CE2, 4DNFIV56OFE3, 4DNFI1UEG1HD, ENCSR244BBG, ENCSR393LOP, GSE44267, ENCSR991JXX, 4DNFIOCW5AEM, 4DNFI9ZWZ5BS, 4DNFIFI6NIKJ, ENCSR933UZH, GSE105028, 4DNFIDBIEXI7, 4DNFIZGCA8AH, GSE116869

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: HL-60,SLK,P3HR-1,CMK,HAP1,U2OS,HeLa-S3,Keratinocytes

Cohesin-DEGs, number of studies: 10

Cohesin-DEGs, study: GSE83870,GSE140651,GSE131581,GSE154086,GSE138937,GSE126635,GSE89799,GSE130558

Cohesin-DEGs, subunit: SA2,WAPL,CTCF,SMC1,Rad21

Tools:

Assay

refGene

Ruler

C21orf91 gene locus

C21orf91 related cohesin sites

C21orf91 related cohesin loop

Deatailed information for gene ENSG00000154642

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