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Basic information

CohesinDB ID: CDBG00009793

Gene Symbol: GABPA

Ensembl ID: ENSG00000154727

Gene locus: chr21:25734569-25772460 Strand: +

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-25375559-25376065, chr21-25383848-25387605, chr21-25387847-25388717, chr21-25395973-25396887, chr21-25399514-25400754, chr21-25401827-25402550, chr21-25420705-25426209, chr21-25572281-25575261, chr21-25576227-25589346, chr21-25589610-25591105, chr21-25591791-25592728, chr21-25595802-25596358, chr21-25600851-25601124, chr21-25606719-25610187, chr21-25614176-25615182, chr21-25624549-25624749, chr21-25626132-25626377, chr21-25626696-25627327, chr21-25638808-25641127, chr21-25642332-25642777, chr21-25646355-25647152, chr21-25647707-25648230, chr21-25731829-25732870, chr21-25733103-25733519, chr21-25733724-25736727, chr21-25750080-25750495, chr21-25756342-25756628, chr21-25770235-25770898, chr21-25800560-25802279, chr21-25850382-25850871, chr21-25857068-25857674, chr21-25862118-25863437, chr21-25865445-25866261, chr21-25866908-25867564, chr21-25868924-25869531, chr21-25871333-25873005, chr21-25949635-25950151, chr21-25952178-25952242, chr21-25953149-25954885, chr21-25957155-25957888, chr21-25959897-25962359, chr21-25962876-25964940, chr21-25965954-25968091, chr21-25969014-25969348, chr21-25970446-25971016, chr21-25972490-25972729, chr21-26150217-26150652, chr21-26151334-26152383, chr21-26153595-26154542, chr21-26154777-26155253, chr21-26158881-26159268, chr21-26159924-26160609, chr21-26162072-26162427, chr21-26162939-26163160, chr21-26163946-26164899, chr21-26165409-26165563, chr21-26165938-26172090, chr21-26172443-26173621, chr21-26375270-26375569, chr21-26377212-26377465, chr21-26385630-26386225, chr21-26388039-26392190, chr21-26405129-26407108, chr21-26408839-26409266, chr21-26409616-26410188, chr21-26411556-26411854, chr21-26412621-26413492, chr21-26447728-26450082, chr21-26451013-26451552, chr21-26451854-26451922, chr21-26469516-26470634, chr21-26470936-26471471, chr21-26527113-26527235, chr21-26529571-26529884, chr21-26542226-26542363, chr21-26543512-26543793, chr21-26545511-26545777, chr21-26546651-26547189, chr21-26677932-26678184, chr21-26681492-26681815, chr21-26684363-26684507, chr21-26686016-26686591, chr21-26690085-26690451, chr21-26698349-26698770, chr21-26702109-26702704, chr21-26709227-26709736, chr21-26714761-26718662, chr21-26718980-26720367, chr21-26721013-26721255, chr21-26721627-26722108, chr21-26801063-26801912, chr21-26805125-26805692, chr21-26806617-26807296, chr21-26810912-26811585, chr21-26814123-26815116, chr21-26815437-26816621, chr21-26816961-26817766, chr21-26819112-26820624, chr21-26824624-26825033, chr21-26826754-26827193, chr21-26832682-26836085, chr21-26836642-26836862, chr21-26837135-26838300, chr21-26839542-26841526, chr21-26841743-26847812, chr21-26848196-26852813,

Co-expression with cohesin genes Rho = 0.7692 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.273
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.874
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,DU145,H1-Mesenchymal,Hepatocyte-H9,GM12878,MSiPS,K-562,HFFc6,PAEC,HeLa-S3,LNCaP,H9-hESC,Primed-hESC,ARPE-19,Hep-G2,Kelly,H1-hESC,HT-1376,Motor-Neuron,NaiveB,SU-DHL-4,NPC-H9,RT-112,Skin-Fibroblast,HFF-hTERT,HAP1

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: 4DNFI8649RQJ, 4DNFI3CFMRID, GSE95015, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIDJ2JZ7Q, 4DNFIMROE6N4, 4DNFITUOMFUQ, 4DNFIE8E4ANZ, ENCSR794RDS, 4DNFI5SUHCGZ, ENCSR545YBD, ENCSR852KQC, GSE84022, GSE120294, ENCSR672RHL, GSE103148, 4DNFI7H4II2V, 4DNFIW8TIFI5, ENCSR410MDC, ENCSR350NJV, ENCSR478BMT, ENCSR732QOH, ENCSR113OIR, GSE69643, ENCSR668RDP, ENCSR381DCY, GSE155380, 4DNFICSTCJQZ, ENCSR981FNA, 4DNFIV239W4L, ENCSR587DSF, GSE80820, 4DNFIE8T8JZ8, 4DNFI9YAVTI1, 4DNFIBT4EAKN, GSE52457, 4DNFI3A3VYWU, ENCSR658RQQ, 4DNFIX4PJKXZ, Direct, 4DNFISPUVQHA, 4DNFI1UEG1HD, GSE101921, GSE108869, 4DNFIEJEFCAM, ENCSR778FXH, 4DNFIQVMVRP6, 4DNFI9ZWZ5BS, ENCSR247RGI, ENCSR110JOO, 4DNFIVJ3IIQL, ENCSR933UZH, GSE105028, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFII84FBKM

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: MCF-7,CMK,U2OS,HeLa-S3,Keratinocytes

Cohesin-DEGs, number of studies: 6

Cohesin-DEGs, study: GSE83870,GSE177045,GSE154086,GSE89799,GSE130558

Cohesin-DEGs, subunit: WAPL,SMC1,Rad21,SA2

Tools:

Assay

refGene

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Ruler

GABPA gene locus

GABPA related cohesin sites

GABPA related cohesin loop

Deatailed information for gene ENSG00000154727

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